Ghetsis challenges the player to fight Black Kyurem B2/White Kyurem W2, preventing it from being captured via a signal from his cane that disrupts the function of Poké Balls. Kyurem then fuses with the stone, creating Black Kyurem B2/White Kyurem W2. This however was part of Ghetsis's plan, and while berating N for causing what will happen to Unova as a result of N's refusal to be his pawn in the previous games, Ghetsis uses the DNA Splicers to forcibly revert Zekrom B2/Reshiram W2 into its stone form. He summons Kyurem to his side and orders it to use Glaciate on the player, only for N to arrive with Zekrom B2/Reshiram W2 and interfere. By the time the player catches up with him, Ghetsis has prepared his plan to freeze all of Unova. He leaves the player to fight the Shadow Triad while he enters the Giant Chasm with Kyurem. After Colress is defeated, Ghetsis confronts the player and angrily denounces Colress as being more interested in science than in Team Plasma's ambitions, even after being appointed as the organization's official leader. In Pokémon Black 2 and White 2, Ghetsis is revealed to be the true mastermind behind the new Team Plasma, which had seemingly been led by Zinzolin, Colress, and the Shadow Triad. For some reason, he has ordered the Shadow Triad to stop looking for him and deliver the player the Adamant, Lustrous, and Griseous Orbs. He has lost everything, including his Pokémon, and only the Shadow Triad are still loyal to him. When the player meets the Shadow Triad for the final time on Marvelous Bridge, they reveal that Ghetsis is currently on the run. He is not seen again in this game.ĭuring the post-game, Cheren reveals that the Shadow Triad had helped Ghetsis to escape. After the battle, Alder and Cheren arrest Ghetsis and take him away. Ghetsis battles the player in a rage, despite N's protest. Alder and Cheren both hear the truth from Ghetsis.
According to a Grunt in the castle, he was even learning of ways to manipulate hearts of people. He reveals that his and Team Plasma's motive for stealing Pokémon was a lie all along and that Ghetsis wanted to ensure that he was the only person in Unova with Pokémon, so he could dominate the region (this was previously foreshadowed by him referring to himself during speeches referring to Team Plasma's goals before correcting himself and saying Team Plasma). After the player defeats N, he reveals he has been using N and revived Zekrom B/ Reshiram W for N to use, and calls N a disappointment.
He later appears at the castle during N's takeover and taunts the player before battling N. He also appears making a similar speech to his one in Accumula Town in Opelucid City. After the player and Alder come to the Relic Castle he is already there and tells them that if they are to battle N, they must retrieve the Light Stone B/ Dark Stone W. After that, he appears at several points in the game, trying to warn the citizens of the oncoming change, and he is often the one that comes to rescue other Seven Sages if they are nearing arrest. Ghetsis first appears in Accumula Town, where he is trying to rally its citizens.